Upconversion Fluorescence Enables Homogeneous Immunoassay in Whole Blood

Upconversion Fluorescence Enables Homogeneous Immunoassay in Whole Blood

A simple homogeneous assay performable directly in whole blood would be useful in clinical diagnostics, but the performance of homogeneous fluorescence-based immunoassays has been severely limited by autofluorescence and strong absorption of ultraviolet and visible light in whole blood.

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Bibliographische Detailangaben
Veröffentlicht in:Clinical chemistry (Baltimore, Md.) Md.), 2007-01, Vol.53 (1), p.145
Hauptverfasser: Kuningas, Katri, Päkkilä, Henna, Telle Ukonaho, Rantanen, Terhi
Format: Artikel
Sprache:eng
Schlagworte:
Blood
Fluorescence
Immunoassay
Immunoassays
Plasma
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Beschreibung
Zusammenfassung:A simple homogeneous assay performable directly in whole blood would be useful in clinical diagnostics, but the performance of homogeneous fluorescence-based immunoassays has been severely limited by autofluorescence and strong absorption of ultraviolet and visible light in whole blood.
ISSN:0009-9147
1530-8561
DOI:10.1373/clinchem.2006.076687