The Effect of Diet and Drugs on Hepatic Microsomal Aminopyrine N-demcthylase Activity in Vitro and Susceptibility to Carbon Tetrachloride in Sheep

Sheep liver microsomal enzymes can N-demethylate aminopyrine to 4-amino-antipyrine. This enzyme activity is unaffected by freezing and thawing. Samples of liver collected from sheep from different flocks had different mean levels of the enzyme activity. Treatment with DDT and phenobarbitone causes a...

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Veröffentlicht in:Research in veterinary science 1972-05, Vol.13 (3), p.245-256
Hauptverfasser: Seawrigiit, A.A., Steele, D.P., Mudie, A.W., Bishop, R.
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Sprache:eng
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