Epidemiology and Outcomes of Granulomatosis With Polyangiitis in Pediatric and Working‐Age Adult Populations In the United States

Epidemiology and Outcomes of Granulomatosis With Polyangiitis in Pediatric and Working‐Age Adult Populations In the United States

Objective The incidence and prevalence of granulomatosis with polyangiitis (GPA) in the US is not well characterized. Owing to its rarity, outcomes data in pediatric‐onset GPA are also lacking. The aims of this study were to describe the epidemiology of GPA and outcomes in GPA patients in the US, an...

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Veröffentlicht in:Arthritis & rheumatology (Hoboken, N.J.) N.J.), 2018-12, Vol.70 (12), p.2067-2076
Hauptverfasser: Panupattanapong, Sirada, Stwalley, Dustin L., White, Andrew J., Olsen, Margaret A., French, Anthony R., Hartman, Mary E.
Format: Artikel
Sprache:eng
Schlagworte:
Adults
Age
Analytics
Children
Complications
Confidence intervals
Epidemiology
Geriatrics
Granulomatosis
Hypogammaglobulinemia
Incidence
Infections
Inflammatory diseases
Leukopenia
Neutropenia
Older people
Patients
Pediatrics
Vein & artery diseases
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Zusammenfassung:Objective The incidence and prevalence of granulomatosis with polyangiitis (GPA) in the US is not well characterized. Owing to its rarity, outcomes data in pediatric‐onset GPA are also lacking. The aims of this study were to describe the epidemiology of GPA and outcomes in GPA patients in the US, and to compare outcomes between pediatric and working‐age adult patients. Methods A retrospective cohort study using the 2006–2014 Truven Health Analytics MarketScan Commercial Claims and Encounters Database was conducted. The incidence and prevalence rates of pediatric and adult GPA (age
ISSN:2326-5191
2326-5205
DOI:10.1002/art.40577