PS-381 Nasal High Frequency Ventilation Is Not More Effective Than Noninvasive Ventilation To Prevent Extubation Failure In Very Preterm Infants

BackgroundIn animal models nasal high frequency oscillatory ventilation appears to provide better lung development and less injury that means it could be protective against repeated need of conventional ventilation. In a randomised study we compared the clinical efficacy of nasal high frequency oscillatory ventilation (nHFOV) and nasal intermittent positive pressure ventilation (NIPPV) in prevention of repeated intubation in preterm infants with very low birth weight.Methods24 preterm infants with birth weight 0.05).ConclusionsIn this study nHFOV was not found to be more effective than NIPPV in prevention of primary extubation failure in preterm infants with very low birth weight.