PS-113 The Association Between Electrical Brain Activity And Arterial Spin Labelling Perfusion Mri In Neonates With Hypoxic-ischaemic Encephalopathy (hie)

PS-113 The Association Between Electrical Brain Activity And Arterial Spin Labelling Perfusion Mri In Neonates With Hypoxic-ischaemic Encephalopathy (hie)

Background and aims(a)EEG predicts outcome in full-term infants with HIE. Recently, increased perfusion in the basal ganglia, detected with arterial spin labelling (ASL), was shown to be related to brain injury1. Our aim was to investigate the relationship between (a)EEG and brain tissue perfusion.M...

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Veröffentlicht in:Archives of disease in childhood 2014-10, Vol.99 (Suppl 2), p.A150-A150
Hauptverfasser: Negro, S, de Vis, JB, Hendrikse, J, Groenendaal, F, de Vries, LS, Petersen, ET, Toet, MC, van Bel, F, Benders, MJNL
Format: Artikel
Sprache:eng
Schlagworte:
Basal ganglia
Brain
Correlation
Cortex
EEG
Encephalopathy
Epilepsy
Hypothermia
Hypoxia
Infants
Ischemia
Magnetic resonance imaging
Neonates
Newborn babies
Perfusion
Sedatives
Spin labeling
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Zusammenfassung:Background and aims(a)EEG predicts outcome in full-term infants with HIE. Recently, increased perfusion in the basal ganglia, detected with arterial spin labelling (ASL), was shown to be related to brain injury1. Our aim was to investigate the relationship between (a)EEG and brain tissue perfusion.Methods20 subjects with HIE, eligible for hypothermia, were enrolled. Four 1-hour periods were selected from the (a)EEG: P1 (4–6 h), P2 (20–24 h), P3 (32–36 h) and P4 (44–48 h). Burst-rate (number of burst/min) and IBI (interburst interval) from the rawEEG, minimum (MIN) amplitude (µV) and the% of time
ISSN:0003-9888
1468-2044
DOI:10.1136/archdischild-2014-307384.407