PS-168 Long-term Renal Complications In The Regional Cohort Of Elbw Children: Correlation Between Results Aquired At The Age Of 7 And Age Of 11 Years

AimAssessment of renal long-term complications in the regional cohort of ELBW children born in 2002–2003.Methods40 children (17 born as ELBW infants and 23 full-term control children randomly selected from one GP office) were assessed at the age of 7 years and next prospectively observed up to 11 years. Serum creatinine, Cystatin C, renal ultrasound and 24-hours ambulatory blood pressure measurements (ABPM) were performed.ResultsMean birthweight of the ELBW group equaled 825g, and mean gestational age equaled 26.5 weeks. Mean renal volume at the age of 7 years was: ELBW group - left kidney (LK) 37ml; right kidney (RK) 40ml, control group - LK 59ml; RK 60ml (p < 0.01 for both kidneys). The increase of renal volume between the age of 7 and 11 was similar in both groups. The volume of kidneys at the age of 11 years was: ELBW group - LK 51ml; RK 56ml, control group - LK 67ml; RK 70ml (p < 0.01 for both kidneys). Calculated eGFR values at the age of 7 and 11 years were similar in both groups (ELBV group at the age of 7 and 11 respectively: 124 vs. 123; control group 127 vs. 114 ml/min*1,72m2). The mean arterial blood pressure (ABPM) increased significantly between both time points (ELBW group: 79 vs. 83, control group: 77 vs. 81 mmHg).ConclusionsThe smaller renal volume observed in the assessed ELBW children at the age of 7 years persisted up to the age of 11 years, however the renal function seems to be intact.