PO-0495 Intravenous Ibuprofen (ibu) Vs Continuous Indomethacin-infusion (ind-inf) For Symptomatic Patent Ductus Arteriosus (pda) Treatment In Newborns

PO-0495 Intravenous Ibuprofen (ibu) Vs Continuous Indomethacin-infusion (ind-inf) For Symptomatic Patent Ductus Arteriosus (pda) Treatment In Newborns

BackgroundIBU is equivalent to IND for PDA-treatment. IBU reduces less cerebral, mesenteric and renal perfusion and platelet function. IND-INF seems to have similar effects on circulation, but the clinical efficacy of this approach is unclear.AimTo compare the efficacy and safety of PDA-treatment us...

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Veröffentlicht in:Archives of disease in childhood 2014-10, Vol.99 (Suppl 2), p.A410
Hauptverfasser: Storring, N, Amess, P, Aiton, N, Bomont, R, Rabe, H, JR Fernandez Alvarez
Format: Artikel
Sprache:eng
Schlagworte:
Birth weight
Chorioamnionitis
Congenital diseases
Coronary vessels
Creatinine
Data processing
Enterocolitis
Ibuprofen
Indomethacin
Infants
Intestine
Intravenous administration
Mechanical ventilation
Mortality
Neonates
Newborn babies
Outcome Measures
Perfusion
Platelets
Renal function
Sodium
Steroid hormones
Vagina
Young Children
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Zusammenfassung:BackgroundIBU is equivalent to IND for PDA-treatment. IBU reduces less cerebral, mesenteric and renal perfusion and platelet function. IND-INF seems to have similar effects on circulation, but the clinical efficacy of this approach is unclear.AimTo compare the efficacy and safety of PDA-treatment using 36-hour IND-INF vs IBU in preterm infants.MethodsRetrospective matched-pair cohort-analysis of infants
ISSN:0003-9888
1468-2044
DOI:10.1136/archdischild-2014-307384.1141