Design, Synthesis, and Anticancer Evaluation of Tetrazole-Fused Benzoxazole Derivatives as Tubulin Binding Agents

A novel series of tetrazole fused benzoxazole derivatives 9a – 9j are synthesized, and their structures are characterized by 1 H and 13 C NMR, and mass spectra. The compounds 9a , 9b , 9g , 9h , and 9j demonstrate the highest activity. The compounds 9b and 9g exhibit good anticancer activity, in par...

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