Transition‐Metal‐Catalyzed Carboxylation Reactions with Carbon Dioxide

Driven by the inherent synthetic potential of CO2 as an abundant, inexpensive and renewable C1 chemical feedstock, the recent years have witnessed renewed interest in devising catalytic CO2 fixations into organic matter. Although the formation of C−C bonds via catalytic CO2 fixation remained rather limited for a long period of time, a close look into the recent literature data indicates that catalytic carboxylation reactions have entered a new era of exponential growth, evolving into a mature discipline that allows for streamlining the synthesis of carboxylic acids, building blocks of utmost relevance in industrial endeavors. These strategies have generally proven broadly applicability and convenient to perform. However, substantial challenges still need to be addressed reinforcing the need to cover metal‐catalyzed carboxylation area in a conceptual and concise manner, delineating the underlying new principles that are slowly emerging in this vibrant area of expertise. With a certain lag time, metal‐catalyzed carboxylation reactions of organic matter with CO2 as C1 feedstock have entered a new era of exponential growth. These C−C bond formations are characterized by their mild conditions and excellent chemo‐ and site selectivity for a wide range of coupling partners, holding promise to streamline synthetic sequences en route to carboxylic acids.