Risk assessments of low-level exposures

The linear extrapolation from large doses to zero that is used in cancer risk assessment in invalid for both chemicals and radiation. Most chemicals are not genotoxic. Animals have natural mechanisms for DNA repair if damage does occur.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 1994-09, Vol.265 (5178), p.1507-1507
1. Verfasser:	Abelson, P H
Format:	Artikel
Sprache:	eng
Schlagworte:	Ames test Animals Cancer Carcinogenicity testing Carcinogenicity Tests - statistics & numerical data Carcinogens - administration & dosage Carcinogens - toxicity DNA Damage DNA Repair Dose-Response Relationship, Drug Editorials Evaluation Health risk assessment Humans Public health Risk Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The linear extrapolation from large doses to zero that is used in cancer risk assessment in invalid for both chemicals and radiation. Most chemicals are not genotoxic. Animals have natural mechanisms for DNA repair if damage does occur.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.7832844