Effect of compound LBK-149 on antiarrhythmic activity of lidocaine in rats with arrhythmias and disturbances in lipid and carbohydrate metabolism
Antiarrhythmic activity of lidocaine during early occlusion and reperfusion arrhythmias decreased in rats with experimental disturbances in lipid and carbohydrate metabolism. The course of additional treatment with compound LBK-149 potentiated antiarrhythmic activity of lidocaine.
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Veröffentlicht in: | Bulletin of experimental biology and medicine 2007-03, Vol.143 (3), p.331-333 |
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container_title | Bulletin of experimental biology and medicine |
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creator | Artem'eva, O V Koryaikina, A V Zor'kina, A V |
description | Antiarrhythmic activity of lidocaine during early occlusion and reperfusion arrhythmias decreased in rats with experimental disturbances in lipid and carbohydrate metabolism. The course of additional treatment with compound LBK-149 potentiated antiarrhythmic activity of lidocaine. |
doi_str_mv | 10.1007/s10517-007-0103-1 |
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subjects | Animals Anti-Arrhythmia Agents - administration & dosage Antiarrhythmics Antioxidants - administration & dosage Arrhythmias, Cardiac - drug therapy Arrhythmias, Cardiac - metabolism Carbohydrate Metabolism - drug effects Drug Synergism Female Lidocaine - administration & dosage Lipid Metabolism - drug effects Lipid Peroxidation - drug effects Male Rats |
title | Effect of compound LBK-149 on antiarrhythmic activity of lidocaine in rats with arrhythmias and disturbances in lipid and carbohydrate metabolism |
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