Poly(Lactic Acid) Fine Fibers Containing a Low Content of Superhydrophilic Multi‐Walled Carbon Nanotube Graphene Oxide Hybrid as Scaffolds for Biological Applications

Herein, polylactic acid containing two different concentrations of superhydrophilic multiwalled carbon nanotube graphene oxide hybrid (MWCNT‐GO, 0.5 wt% and 5 wt%) is rotary‐jet spun. The morphological, thermal, and surface wettability properties are then evaluated. Biological properties, including cytotoxicity, fibroblast cell adhesion, and the overall bioactive effect, are also investigated. It is demonstrated that the thermal behavior is affected by the presence of MWCNT‐GO, as well as the crystallinity. The addition of MWCNT‐GO, even in small amounts, reduces the wettability property of the fibers, making them more hydrophobic. However, biological tests with these fibers show no cytotoxic effect in all fiber sample groups, even when MWCNT‐GO concentration is increased. Therefore, nano‐structured, porous, and biocompatible polymeric scaffolds are obtained, with a high surface area and with notable potential for tissue engineering applications. An interesting and fast way to make fine composite fibers of poly(lactic acid) with incorporated superhydrophilic multiwalled carbon nanotube graphene oxide hybrid (MWCNT‐GO) for biological tissue engineering purposes using rotary‐jet spinning is presented. The inclusion of small amounts of MWCNT‐GO directly affects the thermal, morphological, and biological properties of these fine fibrous scaffolds.