Inertial modulation of hydrophoretic cell sorting and focusing
This paper demonstrates a method of modulating hydrophoretic focusing and sorting by inertial forces in a microfluidic device. At low Reynolds number (Re), hydrophoresis enables size-based sorting by generating specific equilibrium positions for differently sized particles. As increasing Re, hydroph...
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Veröffentlicht in: | Applied physics letters 2014-02, Vol.104 (7) |
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description | This paper demonstrates a method of modulating hydrophoretic focusing and sorting by inertial forces in a microfluidic device. At low Reynolds number (Re), hydrophoresis enables size-based sorting by generating specific equilibrium positions for differently sized particles. As increasing Re, hydrophoresis becomes coupled with inertial effects that bias the equilibrium positions to create a narrow focusing stream. Using this method, we achieved both size-based sorting and sheathless focusing in a device. |
doi_str_mv | 10.1063/1.4866045 |
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At low Reynolds number (Re), hydrophoresis enables size-based sorting by generating specific equilibrium positions for differently sized particles. As increasing Re, hydrophoresis becomes coupled with inertial effects that bias the equilibrium positions to create a narrow focusing stream. Using this method, we achieved both size-based sorting and sheathless focusing in a device.</description><identifier>ISSN: 0003-6951</identifier><identifier>EISSN: 1077-3118</identifier><identifier>DOI: 10.1063/1.4866045</identifier><language>eng</language><publisher>Melville: American Institute of Physics</publisher><subject>Applied physics ; Fluid flow ; Reynolds number</subject><ispartof>Applied physics letters, 2014-02, Vol.104 (7)</ispartof><rights>2014 AIP Publishing LLC.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c323t-8854e0d25408e17e35068c777adadf71d9d0276828e12b189bdaf055a8a0b9cd3</citedby><cites>FETCH-LOGICAL-c323t-8854e0d25408e17e35068c777adadf71d9d0276828e12b189bdaf055a8a0b9cd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids></links><search><creatorcontrib>Song, Seungjeong</creatorcontrib><creatorcontrib>Choi, Sungyoung</creatorcontrib><title>Inertial modulation of hydrophoretic cell sorting and focusing</title><title>Applied physics letters</title><description>This paper demonstrates a method of modulating hydrophoretic focusing and sorting by inertial forces in a microfluidic device. At low Reynolds number (Re), hydrophoresis enables size-based sorting by generating specific equilibrium positions for differently sized particles. As increasing Re, hydrophoresis becomes coupled with inertial effects that bias the equilibrium positions to create a narrow focusing stream. Using this method, we achieved both size-based sorting and sheathless focusing in a device.</description><subject>Applied physics</subject><subject>Fluid flow</subject><subject>Reynolds number</subject><issn>0003-6951</issn><issn>1077-3118</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNotkE1LxDAYhIMoWFcP_oOAJw9d3zdpPnoRZPFjYcGLnkOapG6XbrMm7WH_vZXd0zDMwwwMIfcISwTJn3BZaSmhEhekQFCq5Ij6khQAwEtZC7wmNznvZisY5wV5Xg8hjZ3t6T76qbdjFwcaW7o9-hQP25jC2DnqQt_THGdw-KF28LSNbsqzuSVXre1zuDvrgny_vX6tPsrN5_t69bIpHWd8LLUWVQDPRAU6oApcgNROKWW99a1CX3tgSmo2p6xBXTfetiCE1Raa2nm-IA-n3kOKv1PIo9nFKQ3zpGHIlGKCo5ypxxPlUsw5hdYcUre36WgQzP89Bs35Hv4HmfNWOw</recordid><startdate>20140217</startdate><enddate>20140217</enddate><creator>Song, Seungjeong</creator><creator>Choi, Sungyoung</creator><general>American Institute of Physics</general><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>H8D</scope><scope>L7M</scope></search><sort><creationdate>20140217</creationdate><title>Inertial modulation of hydrophoretic cell sorting and focusing</title><author>Song, Seungjeong ; Choi, Sungyoung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c323t-8854e0d25408e17e35068c777adadf71d9d0276828e12b189bdaf055a8a0b9cd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Applied physics</topic><topic>Fluid flow</topic><topic>Reynolds number</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Song, Seungjeong</creatorcontrib><creatorcontrib>Choi, Sungyoung</creatorcontrib><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Applied physics letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Song, Seungjeong</au><au>Choi, Sungyoung</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Inertial modulation of hydrophoretic cell sorting and focusing</atitle><jtitle>Applied physics letters</jtitle><date>2014-02-17</date><risdate>2014</risdate><volume>104</volume><issue>7</issue><issn>0003-6951</issn><eissn>1077-3118</eissn><abstract>This paper demonstrates a method of modulating hydrophoretic focusing and sorting by inertial forces in a microfluidic device. At low Reynolds number (Re), hydrophoresis enables size-based sorting by generating specific equilibrium positions for differently sized particles. As increasing Re, hydrophoresis becomes coupled with inertial effects that bias the equilibrium positions to create a narrow focusing stream. Using this method, we achieved both size-based sorting and sheathless focusing in a device.</abstract><cop>Melville</cop><pub>American Institute of Physics</pub><doi>10.1063/1.4866045</doi></addata></record> |
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title | Inertial modulation of hydrophoretic cell sorting and focusing |
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