Inertial modulation of hydrophoretic cell sorting and focusing
This paper demonstrates a method of modulating hydrophoretic focusing and sorting by inertial forces in a microfluidic device. At low Reynolds number (Re), hydrophoresis enables size-based sorting by generating specific equilibrium positions for differently sized particles. As increasing Re, hydroph...
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Veröffentlicht in: | Applied physics letters 2014-02, Vol.104 (7) |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | This paper demonstrates a method of modulating hydrophoretic focusing and sorting by inertial forces in a microfluidic device. At low Reynolds number (Re), hydrophoresis enables size-based sorting by generating specific equilibrium positions for differently sized particles. As increasing Re, hydrophoresis becomes coupled with inertial effects that bias the equilibrium positions to create a narrow focusing stream. Using this method, we achieved both size-based sorting and sheathless focusing in a device. |
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ISSN: | 0003-6951 1077-3118 |
DOI: | 10.1063/1.4866045 |