Inertial modulation of hydrophoretic cell sorting and focusing

This paper demonstrates a method of modulating hydrophoretic focusing and sorting by inertial forces in a microfluidic device. At low Reynolds number (Re), hydrophoresis enables size-based sorting by generating specific equilibrium positions for differently sized particles. As increasing Re, hydroph...

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Veröffentlicht in:Applied physics letters 2014-02, Vol.104 (7)
Hauptverfasser: Song, Seungjeong, Choi, Sungyoung
Format: Artikel
Sprache:eng
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Zusammenfassung:This paper demonstrates a method of modulating hydrophoretic focusing and sorting by inertial forces in a microfluidic device. At low Reynolds number (Re), hydrophoresis enables size-based sorting by generating specific equilibrium positions for differently sized particles. As increasing Re, hydrophoresis becomes coupled with inertial effects that bias the equilibrium positions to create a narrow focusing stream. Using this method, we achieved both size-based sorting and sheathless focusing in a device.
ISSN:0003-6951
1077-3118
DOI:10.1063/1.4866045