Synthesis and Antimicrobial Screening of (1-(2,4-Dichlorophenyl)-1H-Pyrazol-4yl (2-Hydroxyphenyl) Methanone and 2- (1-2,4-Dichlorophenyl)- 1H-Pyrazol-4yl) Benzo [D] Oxazole
3-Formylchromone 1 was treated with 2, 4-dichlorophenylhydrazine hydrochloride to get (1-(2,4-dichlorophenyl)-1H-pyrazol-4yl (2-hydroxyphenyl) methanone 2. Compound 2 on treatment with hydroxylamine hydrochloride gave the compound (1-(2,4-dichlorophenyl)-1H-pyrazol-4yl (2-hydroxyphenyl) oxime 3. Com...
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Veröffentlicht in: | Oriental journal of chemistry 2008-09, Vol.24 (3), p.1029 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | 3-Formylchromone 1 was treated with 2, 4-dichlorophenylhydrazine hydrochloride to get (1-(2,4-dichlorophenyl)-1H-pyrazol-4yl (2-hydroxyphenyl) methanone 2. Compound 2 on treatment with hydroxylamine hydrochloride gave the compound (1-(2,4-dichlorophenyl)-1H-pyrazol-4yl (2-hydroxyphenyl) oxime 3. Compound 3 on treatment with POCl3 gave 2- (1-2,4-dichlorophenyl)-1H-pyrazol-4yl) benzo [d] oxazole 4. The structures of compounds have been established on the basis of spectral data. These compounds were screened for their antimicrobial activities. |
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ISSN: | 0970-020X 2231-5039 |