Synthesis and Antimicrobial Screening of (1-(2,4-Dichlorophenyl)-1H-Pyrazol-4yl (2-Hydroxyphenyl) Methanone and 2- (1-2,4-Dichlorophenyl)- 1H-Pyrazol-4yl) Benzo [D] Oxazole

3-Formylchromone 1 was treated with 2, 4-dichlorophenylhydrazine hydrochloride to get (1-(2,4-dichlorophenyl)-1H-pyrazol-4yl (2-hydroxyphenyl) methanone 2. Compound 2 on treatment with hydroxylamine hydrochloride gave the compound (1-(2,4-dichlorophenyl)-1H-pyrazol-4yl (2-hydroxyphenyl) oxime 3. Com...

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Veröffentlicht in:Oriental journal of chemistry 2008-09, Vol.24 (3), p.1029
Hauptverfasser: Narwade, S K, Karale, B K, Jagdhani, S G, Chaudhari, C S, Rindhe, S S
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Sprache:eng
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Zusammenfassung:3-Formylchromone 1 was treated with 2, 4-dichlorophenylhydrazine hydrochloride to get (1-(2,4-dichlorophenyl)-1H-pyrazol-4yl (2-hydroxyphenyl) methanone 2. Compound 2 on treatment with hydroxylamine hydrochloride gave the compound (1-(2,4-dichlorophenyl)-1H-pyrazol-4yl (2-hydroxyphenyl) oxime 3. Compound 3 on treatment with POCl3 gave 2- (1-2,4-dichlorophenyl)-1H-pyrazol-4yl) benzo [d] oxazole 4. The structures of compounds have been established on the basis of spectral data. These compounds were screened for their antimicrobial activities.
ISSN:0970-020X
2231-5039