Three Component Solvent-Free Synthesis and Fungicidal Activity of Substituted Pyrimido [4,5-D] Pyrimidine-2-(1h)-One

Three Component Solvent-Free Synthesis and Fungicidal Activity of Substituted Pyrimido [4,5-D] Pyrimidine-2-(1h)-One

A novel three component condensation of aromatic aldehyde, urea or thiourea and barbituric acid or N,N-1,3-dimethylbarbituric acid was carried out using L-proline as an organo-catalyst under solvent-free microwave conditions. The resulting product, pyrimido [4,5-d] pyrimidine-2-(1H)-one was checked...

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Veröffentlicht in:Oriental journal of chemistry 2010-01, Vol.26 (1), p.307
Hauptverfasser: Shinde, Sandeep V, Jadhav, Wamanrao N, Karade, Nandkisohr N
Format: Artikel
Sprache:eng
Schlagworte:
Condensates
Fungicides
Proline
Solvents
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Zusammenfassung:A novel three component condensation of aromatic aldehyde, urea or thiourea and barbituric acid or N,N-1,3-dimethylbarbituric acid was carried out using L-proline as an organo-catalyst under solvent-free microwave conditions. The resulting product, pyrimido [4,5-d] pyrimidine-2-(1H)-one was checked for the fungicide activity.
ISSN:0970-020X
2231-5039