Synthesis and Characterization of New Series of Imidazolidin-2,4-Dione Derivatives and its Antimicrobial Activity

Synthesis and Characterization of New Series of Imidazolidin-2,4-Dione Derivatives and its Antimicrobial Activity

The synthesis of compound (2) was achieved using cyclization method of compound (1) with ethyl chloro acetate and fused sodium acetate. Compound (2) was underwent mannich reaction to give compound (3a-3f). The Chemical structures were elucidated by IR, 1 HNMR, and elemental analysis. The compounds (...

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Veröffentlicht in:Oriental journal of chemistry 2010-10, Vol.26 (4), p.1425
Hauptverfasser: Kumar, R Surendra, Idhayadhulla, A, Abdul Nasser, A Jamal, Selvin, J
Format: Artikel
Sprache:eng
Schlagworte:
Antiinfectives and antibacterials
Antimicrobial agents
Chemical analysis
Diketones
Organic chemistry
Sodium acetate
Synthesis
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Zusammenfassung:The synthesis of compound (2) was achieved using cyclization method of compound (1) with ethyl chloro acetate and fused sodium acetate. Compound (2) was underwent mannich reaction to give compound (3a-3f). The Chemical structures were elucidated by IR, 1 HNMR, and elemental analysis. The compounds (2) and (3a-3f) have been screened for in vitro antimicrobial action against various strains of bacterial and fungi.Imidazolidin-2, 4-dione, mannich base, antimicrobial activity.
ISSN:0970-020X
2231-5039