Physiological and radio-induced modulations of low-weight globulins in distinct vascular compartments

The main goal was to investigate the profiles of molecular weight globulins lower than albumin in the electrophoresis system in function of the exposition time to gamma radiation. At 72 h post-irradiation, the globulin electrophoretic profiles bellow albumin showed significant radio-induced changes....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of radioanalytical and nuclear chemistry 2018-11, Vol.318 (2), p.1317-1324
Hauptverfasser: Lima, Celso Vieira, de Campos, Tarcísio Passos Ribeiro, Valencia, Carlos Julio Montano, Almeida, Iassudara Garcia
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The main goal was to investigate the profiles of molecular weight globulins lower than albumin in the electrophoresis system in function of the exposition time to gamma radiation. At 72 h post-irradiation, the globulin electrophoretic profiles bellow albumin showed significant radio-induced changes. In addition, the vascular system, specifically the inferior vena cava, kidney, spleen, jugular, hepatic, and pulmonary veins presented a physiological compartmental distribution of globulins. The findings pointed out the radio-induced alterations of the serum globulin concentrations as a late event, possibly related to a radio modulation of the genes’ expression.
ISSN:0236-5731
1588-2780
DOI:10.1007/s10967-018-6188-3