99Mo/99mTc generators based on aluminum molybdate gel matrix prepared by nano method

A procedure for preparation of 99 Mo/ 99m Tc radioisotope generator based on low specific activity neutron activated 99 Mo was developed. Aluminum molybdate(VI)- 99 Mo of high Mo(VI) content (~ 364 mg/g Al 99 Mo) was prepared by mixing low specific activity molybdate(VI)- 99 Mo and aluminum mixture solution with isoamyl alcohol. Al 99 Mo gel matrix was precipitated when the pH of the mixture solution was raised to ~ 5 by addition of NaOH to the mixture. Radiometric measurements indicate the strong fixation of Molybdate(VI)- 99 Mo species in the form of the sparingly insoluble Al 99 Mo gel matrix. The prepared AlMo gel matrix was physiochemically characterized. Al 99 Mo gel matrix was used as a base material for preparation of 99 Mo/ 99m Tc generator. The 99m Tc eluted from 99 Mo/ 99m Tc radioisotope generator was found to have relatively high elution yield (84 ± 2.3%), radionuclidic (≥ 99.99%), radiochemical (98.1 ± 0.9%) and chemical purity.