Chronology of a Difficult Synthesis

Chronology of a Difficult Synthesis

This article describes a short synthesis and many of the difficulties experienced while carrying it out (e.g., low yields, impurities, racemization, nonrepeatable literature preps, etc.). As such, students will be educated in aspects of synthetic organic chemistry that are often down-played, or even...

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Veröffentlicht in:Journal of chemical education 2009-07, Vol.86 (7), p.859
Hauptverfasser: Menger, Fredric M, Sorrells, Jennifer L
Format: Artikel
Sprache:eng
Schlagworte:
Amides
Chemical compounds
Chemical reactions
Chemical synthesis
Chronology
College students
Functional groups
Hydrogen bonding
Laboratory Procedures
Organic Chemistry
Synthesis
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Zusammenfassung:This article describes a short synthesis and many of the difficulties experienced while carrying it out (e.g., low yields, impurities, racemization, nonrepeatable literature preps, etc.). As such, students will be educated in aspects of synthetic organic chemistry that are often down-played, or even not mentioned, in published syntheses.
ISSN:0021-9584
1938-1328
DOI:10.1021/ed086p859