One-Pot Synthesis of 3,5-Disubstituted 1,2,4-Oxadiazoles Using Catalytic System NaOH‒DMSO

One-Pot Synthesis of 3,5-Disubstituted 1,2,4-Oxadiazoles Using Catalytic System NaOH‒DMSO

One-pot convenient process was developed for the production of 3,5-disubstituted 1,2,4-oxadiazoles by reaction of amidoximes with anhydrides or acyl chlorides in a system NaOH‒DMSO. The reaction proceeds at room temperature with high yields.

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Bibliographische Detailangaben
Veröffentlicht in:Russian journal of organic chemistry 2018-08, Vol.54 (8), p.1250-1255
Hauptverfasser: Pankrat’eva, V. E., Sharonova, T. V., Tarasenko, M. V., Baikov, S. V., Kofanov, E. R.
Format: Artikel
Sprache:eng
Schlagworte:
Anhydrides
Catalysis
Chemical synthesis
Chemistry
Chemistry and Materials Science
Organic Chemistry
Oxadiazoles
Sodium hydroxide
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Beschreibung
Zusammenfassung:One-pot convenient process was developed for the production of 3,5-disubstituted 1,2,4-oxadiazoles by reaction of amidoximes with anhydrides or acyl chlorides in a system NaOH‒DMSO. The reaction proceeds at room temperature with high yields.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428018080213