Convenient Synthesis of a Lactone, γ-Butyrolactone

Convenient Synthesis of a Lactone, γ-Butyrolactone

A five-membered cyclic ester, gamma-Butyrolactone, was prepared from GHB using a microscale reflux method. Cyclization yielded a product with a boiling point significantly greater (by 129 °C) than that of the open-chain analogue.

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Veröffentlicht in:Journal of chemical education 1998-01, Vol.75 (1), p.84
Hauptverfasser: Bozak, Richard E, Knittel, J, Hicks, Ronald J
Format: Artikel
Sprache:eng
Schlagworte:
Butyrolactone
Experiments
Organic chemistry
Science education
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Beschreibung
Zusammenfassung:A five-membered cyclic ester, gamma-Butyrolactone, was prepared from GHB using a microscale reflux method. Cyclization yielded a product with a boiling point significantly greater (by 129 °C) than that of the open-chain analogue.
ISSN:0021-9584
1938-1328
DOI:10.1021/ed075p84