Fatal Encephalitic Borna Disease Virus 1 in Solid-Organ Transplant Recipients

Evidence of Borna disease virus 1 infection in humans is limited; in this report, donor-derived Borna virus encephalitis is shown to occur in three solid-organ transplant recipients.

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Veröffentlicht in:	The New England journal of medicine 2018-10, Vol.379 (14), p.1377-1379
Hauptverfasser:	Schlottau, Kore, Forth, Leonie, Angstwurm, Klemens, Höper, Dirk, Zecher, Daniel, Liesche, Friederike, Hoffmann, Bernd, Kegel, Victoria, Seehofer, Daniel, Platen, Sabine, Salzberger, Bernd, Liebert, Uwe G, Niller, Hans-Helmut, Schmidt, Barbara, Matiasek, Kaspar, Riemenschneider, Markus J, Brochhausen, Christoph, Banas, Bernhard, Renders, Lutz, Moog, Philipp, Wunderlich, Silke, Seifert, Christian L, Barreiros, Ana, Rahmel, Axel, Weiss, Jutta, Tappe, Dennis, Herden, Christiane, Schmidt-Chanasit, Jonas, Schwemmle, Martin, Rubbenstroth, Dennis, Schlegel, Jürgen, Pietsch, Corinna, Hoffmann, Donata, Jantsch, Jonathan, Beer, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Animals Borna disease Borna Disease - virology Borna disease virus - genetics Borna disease virus - isolation & purification Brain - diagnostic imaging Brain - pathology Brain - virology Brain research Disease Encephalitis Encephalitis, Viral - virology Fatal Outcome Female Genomes Humans Infections Kidney Transplantation Liver Transplantation Magnetic Resonance Imaging Male Phylogeny RNA, Viral - isolation & purification Transplants & implants Transplants - virology Zoonoses Zoonoses - virology
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Beschreibung
Zusammenfassung:	Evidence of Borna disease virus 1 infection in humans is limited; in this report, donor-derived Borna virus encephalitis is shown to occur in three solid-organ transplant recipients.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMc1803115