Mathematical analysis and numerical simulations for the HSP70 synthesis model

The heat shock proteins (HSPs) protect the other proteins in the process of folding under stressful conditions such as oxygen deprivation, hypothermy or presence of alcohol. They have also an important role in tumour invasion. In this paper, the existence, uniqueness and permanence properties for th...

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Veröffentlicht in:Journal of mathematical chemistry 2018-11, Vol.56 (10), p.3089-3114
Hauptverfasser: Meral, Gülnihal, Pelen, Neslihan Nesliye
Format: Artikel
Sprache:eng
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Zusammenfassung:The heat shock proteins (HSPs) protect the other proteins in the process of folding under stressful conditions such as oxygen deprivation, hypothermy or presence of alcohol. They have also an important role in tumour invasion. In this paper, the existence, uniqueness and permanence properties for the solution of the mathematical model which focuses on the synthesis of HSP70 is proved. Moreover the numerical simulations are performed by using FDM, namely a combination of backward and forward Euler methods, and the results confirm the expected behaviour of the solution.
ISSN:0259-9791
1572-8897
DOI:10.1007/s10910-018-0934-1