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To evaluate the efficacy of a single 60-mg dose of pyridostigmine bromide, alone or in combination with a subthreshold (2.5 mg) or suprathreshold (5 mg) dose of midodrine hydrochloride, compared with placebo. After 1 day of baseline measurements, patients were given 4 treatments (3 active treatments...

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Veröffentlicht in:JAMA : the journal of the American Medical Association 2006-06, Vol.295 (22), p.2585
1. Verfasser: Brender, Erin
Format: Artikel
Sprache:eng
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Zusammenfassung:To evaluate the efficacy of a single 60-mg dose of pyridostigmine bromide, alone or in combination with a subthreshold (2.5 mg) or suprathreshold (5 mg) dose of midodrine hydrochloride, compared with placebo. After 1 day of baseline measurements, patients were given 4 treatments (3 active treatments 60 mg of pyridostigmine bromide; 60 mg of pyridostigmine bromide and 2.5 mg of midodrine hydrochloride; 60 mg of pyridostigmine bromide and 5 mg of midodrine hydrochloride 1 and a placebo) in random order on successive days.
ISSN:0098-7484
1538-3598