The WHI Estrogen-Alone Trial—Do Things Look Any Better?
The findings of the Heart and Estrogen/progestin Replacement Study and Women's Health Initiative (WHI) led the FDA to recommend that estrogen preparations not be used to prevent coronary heart disease or considered first-line therapy for prevention of osteoporosis. In summary, the WHI trials su...
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Veröffentlicht in: | JAMA : the journal of the American Medical Association 2004-04, Vol.291 (14), p.1769-1771 |
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creator | Hulley, Stephen B Grady, Deborah |
description | The findings of the Heart and Estrogen/progestin Replacement Study and Women's Health Initiative (WHI) led the FDA to recommend that estrogen preparations not be used to prevent coronary heart disease or considered first-line therapy for prevention of osteoporosis. In summary, the WHI trials suggest that estrogen alone does not have advantages over estrogen plus progestin for treating post-menopausal women. |
doi_str_mv | 10.1001/jama.291.14.1769 |
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source | MEDLINE; American Medical Association Journals |
subjects | Clinical trials Coronary Disease - epidemiology Coronary Disease - prevention & control Estrogen Replacement Therapy - adverse effects Estrogens Estrogens - adverse effects Estrogens - therapeutic use Estrogens, Conjugated (USP) - adverse effects Estrogens, Conjugated (USP) - therapeutic use Female Hormone replacement therapy Humans Menopause Postmenopause Risk Assessment |
title | The WHI Estrogen-Alone Trial—Do Things Look Any Better? |
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