Hailey-Hailey disease is caused by mutations in ATP2C1encoding a novel Ca2+ pump

Hailey-Hailey disease is caused by mutations in ATP2C1encoding a novel Ca2+ pump

Hailey-Hailey disease (HHD) is an autosomal dominant skin disorder characterized by suprabasal cell separation (acantholysis) of the epidermis. Previous genetic linkage studies localized the gene to a 5 cM interval on human chromosome 3q21. After reducing the disease critical region to

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Veröffentlicht in:Human molecular genetics 2000-04, Vol.9 (7), p.1131
Hauptverfasser: Sudbrak, Ralf, Brown, Joanna, Dobson-Stone, Carol, Carter, Simon, Ramser, Juliane, White, Jacqueline, Healy, Eugene, Dissanayake, Manel, Larregue, Marc, Perrussel, Marc, Lehrach, Hans, Munro, Colin S, Strachan, Tom, Burge, Susan, Hovnanian, Alain, Monaco, Anthony P
Format: Artikel
Sprache:eng
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Zusammenfassung:Hailey-Hailey disease (HHD) is an autosomal dominant skin disorder characterized by suprabasal cell separation (acantholysis) of the epidermis. Previous genetic linkage studies localized the gene to a 5 cM interval on human chromosome 3q21. After reducing the disease critical region to
ISSN:0964-6906
1460-2083