Antioxidant, anti-inflammatory, and antiproliferative activity of extracts obtained from Tabebuia Rosea (Bertol.) DC

90%). The best antiproliferative activity was displayed by the inner bark chloroform extract against HepG2 (selectivity index [SI] = 5.50) and B16F10 (SI = 3.18) cell lines. Conclusion: These results demonstrate the potential biological activity of T. rosea extracts. Abbreviations used: DPPH: 2,2-di...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Pharmacognosy Magazine 2018-04, Vol.14 (55), p.25-31
Hauptverfasser:	Jiménez-González, Francisco, Vélez-Gómez, Jenny, Melchor-Moncada, Jhon, Veloza, Luz, Sepúlveda-Arias, Juan
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-inflammatory agents Antineoplastic agents Antioxidants Antioxidants (Nutrients) Biological activity Chemical properties Cytotoxicity Free radicals Health aspects Inflammatory diseases Leaves Medicinal plants Metabolites Pau d'arco Pharmacognosy Pharmacological research Phytochemicals Plant extracts Rodents Tumor necrosis factor-TNF
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	90%). The best antiproliferative activity was displayed by the inner bark chloroform extract against HepG2 (selectivity index [SI] = 5.50) and B16F10 (SI = 3.18) cell lines. Conclusion: These results demonstrate the potential biological activity of T. rosea extracts. Abbreviations used: DPPH: 2,2-diphenyl-1-picrylhydrazyl; ORAC: Oxygen radical absorbance capacity; LPS: Lipopolysaccharide; NO: Nitric oxide; TNF-a: Tumor Necrosis Factor Alpha; PGE2: Prostaglandin E2; TAC: Total antioxidant content; MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide.
ISSN:	0973-1296 0976-4062
DOI:	10.4103/pm.pm_624_17