Cobalt(II)‐Catalyzed N‐Acylation of Amines through a Transamidation Reaction

A practical protocol has been developed for a Co(OAc)2·4H2O‐catalyzed transamidation reaction. The reaction gives high yields and uses N,N‐dimethylformamide and other amides as carbonyl sources. The protocol is rapid and simple, and it does not require any acids, bases, ligands, or other additives. It works well for a wide range of primary, secondary, and heterocyclic amines. An efficient, practical, CoII‐catalyzed N‐acylation reaction of various amines using readily available and inexpensive DMF and other amides as carbonyl sources is described.