Glucocorticoid-attenuated response genes induced in the lung during endotoxemia

Glucocorticoid-attenuated response genes induced in the lung during endotoxemia

Cytokines and other mediators whose induction in inflammatory lung disease is attenuated by glucocorticoids are potential targets for development of selective anti-inflammatory treatments. Smith et al refer to genes with these regulatory characteristics as glucocorticoid-attenuated response genes, o...

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Veröffentlicht in:American journal of physiology. Lung cellular and molecular physiology 2002-09, Vol.27 (3), p.L636-L647
Hauptverfasser: SMITH, Jeffrey B, NGUYEN, Tam T, HUGHES, Heather J, HERSCHMAN, Harvey R, WIDNEY, Daniel P, BUI, Kim C, ROVAI, Leonor E
Format: Artikel
Sprache:eng
Schlagworte:
Bacterial diseases
Biological and medical sciences
Cytokines
Experimental bacterial diseases and models
Genes
Infectious diseases
Lungs
Medical sciences
Respiratory diseases
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Zusammenfassung:Cytokines and other mediators whose induction in inflammatory lung disease is attenuated by glucocorticoids are potential targets for development of selective anti-inflammatory treatments. Smith et al refer to genes with these regulatory characteristics as glucocorticoid-attenuated response genes, or GARGs.
ISSN:1040-0605
1522-1504