Recombinant GM-CSF reduces lung injury and mortality during neutropenic Candida sepsis
A comprehensive immunophysiological model of subacute hematogenous infection with 10 million yeast-phase Candida albicans in chronically instrumented antibiotic-treated rats was used to examine the impact of murine recombinant murine granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF...
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| Veröffentlicht in: | American journal of physiology. Lung cellular and molecular physiology 1994-05, Vol.10 (5), p.L561-L568 |
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| container_end_page | L568 |
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| container_issue | 5 |
| container_start_page | L561 |
| container_title | American journal of physiology. Lung cellular and molecular physiology |
| container_volume | 10 |
| creator | LECHNER, A. J LAMPRECH, K. E POTTHOFF, L. H TREDWAY, T. L MATUSCHAK, G. M |
| description | A comprehensive immunophysiological model of subacute hematogenous infection with 10 million yeast-phase Candida albicans in chronically instrumented antibiotic-treated rats was used to examine the impact of murine recombinant murine granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF reduces lung injury and mortality. |
| format | Article |
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J ; LAMPRECH, K. E ; POTTHOFF, L. H ; TREDWAY, T. L ; MATUSCHAK, G. M</creator><creatorcontrib>LECHNER, A. J ; LAMPRECH, K. E ; POTTHOFF, L. H ; TREDWAY, T. L ; MATUSCHAK, G. M</creatorcontrib><description>A comprehensive immunophysiological model of subacute hematogenous infection with 10 million yeast-phase Candida albicans in chronically instrumented antibiotic-treated rats was used to examine the impact of murine recombinant murine granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF reduces lung injury and mortality.</description><identifier>ISSN: 1040-0605</identifier><identifier>EISSN: 1522-1504</identifier><identifier>CODEN: APLPE7</identifier><language>eng</language><publisher>Bethesda, MD: American Physiological Society</publisher><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antifungal agents ; Biochemistry ; Biological and medical sciences ; Injuries ; Lungs ; Medical sciences ; Mortality ; Pharmacology. 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M</creatorcontrib><title>Recombinant GM-CSF reduces lung injury and mortality during neutropenic Candida sepsis</title><title>American journal of physiology. Lung cellular and molecular physiology</title><description>A comprehensive immunophysiological model of subacute hematogenous infection with 10 million yeast-phase Candida albicans in chronically instrumented antibiotic-treated rats was used to examine the impact of murine recombinant murine granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF reduces lung injury and mortality.</description><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antifungal agents</subject><subject>Biochemistry</subject><subject>Biological and medical sciences</subject><subject>Injuries</subject><subject>Lungs</subject><subject>Medical sciences</subject><subject>Mortality</subject><subject>Pharmacology. 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Drug treatments</topic><topic>Rodents</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LECHNER, A. J</creatorcontrib><creatorcontrib>LAMPRECH, K. E</creatorcontrib><creatorcontrib>POTTHOFF, L. H</creatorcontrib><creatorcontrib>TREDWAY, T. L</creatorcontrib><creatorcontrib>MATUSCHAK, G. M</creatorcontrib><collection>Pascal-Francis</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Physical Education Index</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>American journal of physiology. Lung cellular and molecular physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LECHNER, A. J</au><au>LAMPRECH, K. E</au><au>POTTHOFF, L. H</au><au>TREDWAY, T. L</au><au>MATUSCHAK, G. M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recombinant GM-CSF reduces lung injury and mortality during neutropenic Candida sepsis</atitle><jtitle>American journal of physiology. Lung cellular and molecular physiology</jtitle><date>1994-05-01</date><risdate>1994</risdate><volume>10</volume><issue>5</issue><spage>L561</spage><epage>L568</epage><pages>L561-L568</pages><issn>1040-0605</issn><eissn>1522-1504</eissn><coden>APLPE7</coden><abstract>A comprehensive immunophysiological model of subacute hematogenous infection with 10 million yeast-phase Candida albicans in chronically instrumented antibiotic-treated rats was used to examine the impact of murine recombinant murine granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF reduces lung injury and mortality.</abstract><cop>Bethesda, MD</cop><pub>American Physiological Society</pub></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1040-0605 |
| ispartof | American journal of physiology. Lung cellular and molecular physiology, 1994-05, Vol.10 (5), p.L561-L568 |
| issn | 1040-0605 1522-1504 |
| language | eng |
| recordid | cdi_proquest_journals_210938603 |
| source | Alma/SFX Local Collection |
| subjects | Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal agents Biochemistry Biological and medical sciences Injuries Lungs Medical sciences Mortality Pharmacology. Drug treatments Rodents |
| title | Recombinant GM-CSF reduces lung injury and mortality during neutropenic Candida sepsis |
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