Endothelin-1 is elevated in monocrotaline pulmonary hypertension
Theses studies document striking pulmonary vasoconstrictor response to nitric oxide synthase (NOS) inhibition in monocrotaline (MCT) pulmonary hypertension in rats. This constriction is caused by elevated endothelin (ET)-1 production acting on ETA receptors.
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Veröffentlicht in: | American journal of physiology. Lung cellular and molecular physiology 1999-02, Vol.20 (2), p.L304-L310 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Theses studies document striking pulmonary vasoconstrictor response to nitric oxide synthase (NOS) inhibition in monocrotaline (MCT) pulmonary hypertension in rats. This constriction is caused by elevated endothelin (ET)-1 production acting on ETA receptors. |
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ISSN: | 1040-0605 1522-1504 |