Human bronchial epithelial cells express PAR-2 with different sensitivity to thermolysin

Human bronchial epithelial cells express PAR-2 with different sensitivity to thermolysin

Protease-activated receptor-2 (PAR-2) plays a role in inflammatory reactions in airway physiology. Proteases cleaving the extracellular NH2 terminus of receptors activate or inactivate PAR, thus possessing a therapeutic potential.

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Bibliographische Detailangaben
Veröffentlicht in:American journal of physiology. Lung cellular and molecular physiology 2002-06, Vol.26 (6), p.L1339
Hauptverfasser: Ubl, Joachim J, Grishina, Zoryana V, Sukhomlin, Tatiana K, Welte, Tobias
Format: Artikel
Sprache:eng
Schlagworte:
Cells
Respiratory system
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Beschreibung
Zusammenfassung:Protease-activated receptor-2 (PAR-2) plays a role in inflammatory reactions in airway physiology. Proteases cleaving the extracellular NH2 terminus of receptors activate or inactivate PAR, thus possessing a therapeutic potential.
ISSN:1040-0605
1522-1504