Lung function, permeability, and surfactant composition in oleic acid-induced acute lung injury in rats

Although acute lung injury (ALI) is associated with inflammation and surfactant dysfunction, the precise sequence of these changes remains poorly described. We used oleic acid to study the pathogenesis of ALI in spontaneously breathing anesthetized rats.

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Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2000-12, Vol.23 (6), p.L1091-L1102
Hauptverfasser:	DAVIDSON, Kate G, BERSTEN, Andrew D, BARR, Heather A, DOWLING, Kay D, NICHOLAS, Terence E, DOYLE, Ian R
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Injuries Lungs Medical sciences Permeability Pneumology Proteins Respiratory system : syndromes and miscellaneous diseases Rodents
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Beschreibung
Zusammenfassung:	Although acute lung injury (ALI) is associated with inflammation and surfactant dysfunction, the precise sequence of these changes remains poorly described. We used oleic acid to study the pathogenesis of ALI in spontaneously breathing anesthetized rats.
ISSN:	1040-0605 1522-1504