Increased expression of heat shock protein-70 protects A549 cells against hyperoxia

Increased expression of heat shock protein-70 protects A549 cells against hyperoxia

Acute and chronic lung injury secondary to hyperoxia remains an important complication in critically ill patients, and, consequently, there is interest in developing strategies to protect the lung against hyperoxia. Heat shock proteins (HSPs) confer protection against a broad array of cytotoxic agen...

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Veröffentlicht in:American journal of physiology. Lung cellular and molecular physiology 1998-10, Vol.19 (4), p.L836-L841
Hauptverfasser: WONG, H. R, MENENDEZ, I. Y, RYAN, M. A, DENENBERG, A. G, WISPE, J. R
Format: Artikel
Sprache:eng
Schlagworte:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Cells
Emergency and intensive respiratory care
Injuries
Intensive care medicine
Lungs
Medical sciences
Proteins
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Zusammenfassung:Acute and chronic lung injury secondary to hyperoxia remains an important complication in critically ill patients, and, consequently, there is interest in developing strategies to protect the lung against hyperoxia. Heat shock proteins (HSPs) confer protection against a broad array of cytotoxic agents.
ISSN:1040-0605
1522-1504