Metal-dependent expression of ferritin and lactoferrin by respiratory epithelial cells

Increased availability of catalytically active metal has been associated with anoxidative injury. The sequestration of transition metals within intracellular ferritin confers an antioxidant function to this protein. Such storage by ferritin requires that the metal be transported across a cell membra...

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Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 1998-05, Vol.18 (5), p.L728-L736
Hauptverfasser:	GHIO, A. J, CARTER, J. D, SAMET, J. M, REED, W, QUAY, J, DAILEY, L. A, RICHARDS, J. H, DEVLIN, R. B
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy & physiology Biological and medical sciences Free radicals Fundamental and applied biological sciences. Psychology Gene expression Lungs Metals Molecular and cellular biology Molecular genetics Proteins
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Zusammenfassung:	Increased availability of catalytically active metal has been associated with anoxidative injury. The sequestration of transition metals within intracellular ferritin confers an antioxidant function to this protein. Such storage by ferritin requires that the metal be transported across a cell membrane.
ISSN:	1040-0605 1522-1504