Oxidant stress stimulates mucin secretion and PLC in airway epithelium via a nitric oxide-dependent mechanism

A study investigated mechanisms of reactive oxygen species (ROS)-induced mucin secretion by guinea pig tracheal epithelial (GPTE) cells in primary culture and ROS-induced activation of the second messenger-producing enzyme phospholipase C (PLC), in GPTE cells and in a virally transformed cell line d...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 1996-11, Vol.15 (5), p.L854-L861
Hauptverfasser:	WRIGHT, D. T, FISCHER, B. M, LI, C, ROCHELLE, L. G, AKLEY, N. J, ADLER, K. B
Format:	Artikel
Sprache:	eng
Schlagworte:	Air breathing Anatomy & physiology Biological and medical sciences Cells Fundamental and applied biological sciences. Psychology Lungs Mucous membrane Oxidation Respiratory system: anatomy, metabolism, gas exchange, ventilatory mechanics, respiratory hemodynamics Rodents Vertebrates: respiratory system
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A study investigated mechanisms of reactive oxygen species (ROS)-induced mucin secretion by guinea pig tracheal epithelial (GPTE) cells in primary culture and ROS-induced activation of the second messenger-producing enzyme phospholipase C (PLC), in GPTE cells and in a virally transformed cell line derived from human bronchial epithelium.
ISSN:	1040-0605 1522-1504