Pertussis toxin attenuates platelet-activating factor-induced pulmonary hemodynamic alterations in pigs

Pertussis toxin was administered to conscious pigs approximately 48 hours before bolus infusions of platelet-activating factor (PAF) to determine whether PAF-induced release of cyclooxygenase products might be dependent on G proteins in vivo. Results are discussed.

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Veröffentlicht in:American journal of physiology. Lung cellular and molecular physiology 1993-03, Vol.8 (3), p.L213-L221
Hauptverfasser: OLSON, N. C, KRUSE-ELLIOTT, K. T, WHORTON, A. R, DODAM, J. R
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Sprache:eng
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Zusammenfassung:Pertussis toxin was administered to conscious pigs approximately 48 hours before bolus infusions of platelet-activating factor (PAF) to determine whether PAF-induced release of cyclooxygenase products might be dependent on G proteins in vivo. Results are discussed.
ISSN:1040-0605
1522-1504