PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells
A study was conducted to test the hypothesis that phosphatidylinositol 3-kinase activation is both necessary and sufficient to mediate human pulmonary vascular smooth muscle cell proliferation and migration.
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| Veröffentlicht in: | American journal of physiology. Lung cellular and molecular physiology 2002-08, Vol.27 (2), p.L354-L363 |
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| container_end_page | L363 |
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| container_issue | 2 |
| container_start_page | L354 |
| container_title | American journal of physiology. Lung cellular and molecular physiology |
| container_volume | 27 |
| creator | GONCHAROVA, Elena A AMMIT, Alaina J IRANI, Carla CARROLL, Richard G ESZTERHAS, Andrew J PANETTIERI, Reynold A KRYMSKAYA, Vera P |
| description | A study was conducted to test the hypothesis that phosphatidylinositol 3-kinase activation is both necessary and sufficient to mediate human pulmonary vascular smooth muscle cell proliferation and migration. |
| format | Article |
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Lung cellular and molecular physiology</title><description>A study was conducted to test the hypothesis that phosphatidylinositol 3-kinase activation is both necessary and sufficient to mediate human pulmonary vascular smooth muscle cell proliferation and migration.</description><subject>Atherosclerosis (general aspects, experimental research)</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Cardiology. Vascular system</subject><subject>Enzymes</subject><subject>Hypertension</subject><subject>Lungs</subject><subject>Medical sciences</subject><subject>Pneumology</subject><subject>Proteins</subject><subject>Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. 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Vascular system</topic><topic>Enzymes</topic><topic>Hypertension</topic><topic>Lungs</topic><topic>Medical sciences</topic><topic>Pneumology</topic><topic>Proteins</topic><topic>Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. 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| fulltext | fulltext |
| identifier | ISSN: 1040-0605 |
| ispartof | American journal of physiology. Lung cellular and molecular physiology, 2002-08, Vol.27 (2), p.L354-L363 |
| issn | 1040-0605 1522-1504 |
| language | eng |
| recordid | cdi_proquest_journals_210883153 |
| source | American Physiological Society; EZB-FREE-00999 freely available EZB journals |
| subjects | Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Enzymes Hypertension Lungs Medical sciences Pneumology Proteins Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases |
| title | PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells |
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