PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells

A study was conducted to test the hypothesis that phosphatidylinositol 3-kinase activation is both necessary and sufficient to mediate human pulmonary vascular smooth muscle cell proliferation and migration.

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Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2002-08, Vol.27 (2), p.L354-L363
Hauptverfasser:	GONCHAROVA, Elena A, AMMIT, Alaina J, IRANI, Carla, CARROLL, Richard G, ESZTERHAS, Andrew J, PANETTIERI, Reynold A, KRYMSKAYA, Vera P
Format:	Artikel
Sprache:	eng
Schlagworte:	Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Enzymes Hypertension Lungs Medical sciences Pneumology Proteins Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases
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Beschreibung
Zusammenfassung:	A study was conducted to test the hypothesis that phosphatidylinositol 3-kinase activation is both necessary and sufficient to mediate human pulmonary vascular smooth muscle cell proliferation and migration.
ISSN:	1040-0605 1522-1504