Potassium channels regulate tone in rat pulmonary veins

Intrapulmonary veins (PVs) contribute to pulmonary vascular resistance, but the mechanisms controlling PV tone are poorly understood. Although smooth muscle cell (SMC) K+ channels regulate tone in most vascular beds, their role in PV tone is unknown.

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Veröffentlicht in:American journal of physiology. Lung cellular and molecular physiology 2001-06, Vol.24 (6), p.L1138-L1147
Hauptverfasser: MICHELAKIS, Evangelos D, WEIR, E. Kenneth, XICHEN WU, NSAIR, Ali, WAITE, Ross, HASHIMOTO, Kyoko, PUTTAGUNTA, Lakshmi, KNAUS, Hans Gunther, ARCHER, Stephen L
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container_issue 6
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container_title American journal of physiology. Lung cellular and molecular physiology
container_volume 24
creator MICHELAKIS, Evangelos D
WEIR, E. Kenneth
XICHEN WU
NSAIR, Ali
WAITE, Ross
HASHIMOTO, Kyoko
PUTTAGUNTA, Lakshmi
KNAUS, Hans Gunther
ARCHER, Stephen L
description Intrapulmonary veins (PVs) contribute to pulmonary vascular resistance, but the mechanisms controlling PV tone are poorly understood. Although smooth muscle cell (SMC) K+ channels regulate tone in most vascular beds, their role in PV tone is unknown.
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source American Physiological Society; EZB-FREE-00999 freely available EZB journals
subjects Biological and medical sciences
Blood vessels
Circulatory system
Immune system
Medical sciences
Muscular system
Pneumology
Potassium
Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases
Rodents
title Potassium channels regulate tone in rat pulmonary veins
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