Potassium channels regulate tone in rat pulmonary veins

Intrapulmonary veins (PVs) contribute to pulmonary vascular resistance, but the mechanisms controlling PV tone are poorly understood. Although smooth muscle cell (SMC) K+ channels regulate tone in most vascular beds, their role in PV tone is unknown.

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Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2001-06, Vol.24 (6), p.L1138-L1147
Hauptverfasser:	MICHELAKIS, Evangelos D, WEIR, E. Kenneth, XICHEN WU, NSAIR, Ali, WAITE, Ross, HASHIMOTO, Kyoko, PUTTAGUNTA, Lakshmi, KNAUS, Hans Gunther, ARCHER, Stephen L
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood vessels Circulatory system Immune system Medical sciences Muscular system Pneumology Potassium Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases Rodents
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Beschreibung
Zusammenfassung:	Intrapulmonary veins (PVs) contribute to pulmonary vascular resistance, but the mechanisms controlling PV tone are poorly understood. Although smooth muscle cell (SMC) K+ channels regulate tone in most vascular beds, their role in PV tone is unknown.
ISSN:	1040-0605 1522-1504