Microwave‐Assisted Synthesis of Antimicrobial Agents Containing Carbazole and Thiazole Moieties

An efficient synthesis of new derivatives of carbazole incorporated with thiazole moiety via the reaction of carbazole thiosemicarbazone with hydrazonoyl chloride under microwave irradiation. The spectral results and the electronic absorption data proved the postulated structures of the resulting co...

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Veröffentlicht in:Journal of heterocyclic chemistry 2018-09, Vol.55 (9), p.2099-2106
Hauptverfasser: Jasass, Rabab S., Alshehrei, Fatimah, Farghaly, Thoraya A.
Format: Artikel
Sprache:eng
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Zusammenfassung:An efficient synthesis of new derivatives of carbazole incorporated with thiazole moiety via the reaction of carbazole thiosemicarbazone with hydrazonoyl chloride under microwave irradiation. The spectral results and the electronic absorption data proved the postulated structures of the resulting compounds. The starting thiosemicarbazone and all the new derivatives were evaluated against two fungi, four G+ bacteria and G− bacteria. The results obtained explore the high potency of some of the tested compounds compared with the employed standard bactericides and fungicides.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.3253