TRANSITION PROBABILITIES OF CHRONIC KIDNEY DISEASE IN A CARDIOVASCULAR RISK MANAGEMENT PROGRAM

OBJECTIVES: "De Todo Corazon" (DTC) is a cardiovascular risk management program. The aim of this study was to estimate the transition probabilities of Chronic Kidney Disease (CKD) in patients under program care. METHODS: We followed up a cohort of 55,915 patients with hypertension and / or...

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Veröffentlicht in:Value in health 2017-05, Vol.20 (5), p.A348
Hauptverfasser: Guzman, N Alvis, Machado, P Miranda, Mejia, F Salcedo, Wilches, J Paz, Restrepo, F De la Hoz
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container_end_page
container_issue 5
container_start_page A348
container_title Value in health
container_volume 20
creator Guzman, N Alvis
Machado, P Miranda
Mejia, F Salcedo
Wilches, J Paz
Restrepo, F De la Hoz
description OBJECTIVES: "De Todo Corazon" (DTC) is a cardiovascular risk management program. The aim of this study was to estimate the transition probabilities of Chronic Kidney Disease (CKD) in patients under program care. METHODS: We followed up a cohort of 55,915 patients with hypertension and / or diabetes mellitus between June 2014 and December 2015. The glomerular filtration rate (GFR) was calculated using the Cockcroft Gault formula. A diagnosis of CKD in GFR 65 years and 66.5% were female. The prevalence of hypertension and diabetes mellitus was 96.5% and 36.1%, respectively. At 18 months follow-up, 3.0% of patients with hypertension without diabetes mellitus progressed to CKD (Stage 3B, 4 and 5). 3.8% of patients with hypertension and diabetes mellitus progressed to CKD. The risk of progression of CKD was significantly higher in patients with hypertension with diabetes mellitus (OR: 1.30 CI 95% 1.17-1.45). CONCLUSIONS: The presence of hypertension with diabetes mellitus was significantly associated with progression to CKD over a period of 18 months, independent of baseline GFR.
doi_str_mv 10.1016/j.jval.2017.05.005
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The aim of this study was to estimate the transition probabilities of Chronic Kidney Disease (CKD) in patients under program care. METHODS: We followed up a cohort of 55,915 patients with hypertension and / or diabetes mellitus between June 2014 and December 2015. The glomerular filtration rate (GFR) was calculated using the Cockcroft Gault formula. A diagnosis of CKD in GFR &lt;60 ml/ min/ 1.73m2 at the end of follow-up was considered. To estimate the progression of CKD, the percentages of patients at each stage of kidney disease were estimated according to the Kidney Disease Improving Global Outcomes Guidelines (KDIGO), at the beginning and at the end of follow-up. To establish association between arterial hypertension and diabetes mellitus with progression of CKD, the Odds Ratio (OR) was estimated. RESULTS: 50.1% of the patients were&gt; 65 years and 66.5% were female. The prevalence of hypertension and diabetes mellitus was 96.5% and 36.1%, respectively. At 18 months follow-up, 3.0% of patients with hypertension without diabetes mellitus progressed to CKD (Stage 3B, 4 and 5). 3.8% of patients with hypertension and diabetes mellitus progressed to CKD. The risk of progression of CKD was significantly higher in patients with hypertension with diabetes mellitus (OR: 1.30 CI 95% 1.17-1.45). CONCLUSIONS: The presence of hypertension with diabetes mellitus was significantly associated with progression to CKD over a period of 18 months, independent of baseline GFR.</description><identifier>ISSN: 1098-3015</identifier><identifier>EISSN: 1524-4733</identifier><identifier>DOI: 10.1016/j.jval.2017.05.005</identifier><language>eng</language><publisher>Lawrenceville: Elsevier Science Ltd</publisher><subject>Cardiovascular disease ; Cardiovascular diseases ; Diabetes ; Diabetes mellitus ; Glomerular filtration rate ; Health promotion ; Hypertension ; Kidney diseases ; Kidneys ; Medical diagnosis ; Patients ; Probability ; Risk management</subject><ispartof>Value in health, 2017-05, Vol.20 (5), p.A348</ispartof><rights>Copyright Elsevier Science Ltd. 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At 18 months follow-up, 3.0% of patients with hypertension without diabetes mellitus progressed to CKD (Stage 3B, 4 and 5). 3.8% of patients with hypertension and diabetes mellitus progressed to CKD. The risk of progression of CKD was significantly higher in patients with hypertension with diabetes mellitus (OR: 1.30 CI 95% 1.17-1.45). 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source Elsevier ScienceDirect Journals Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Applied Social Sciences Index & Abstracts (ASSIA)
subjects Cardiovascular disease
Cardiovascular diseases
Diabetes
Diabetes mellitus
Glomerular filtration rate
Health promotion
Hypertension
Kidney diseases
Kidneys
Medical diagnosis
Patients
Probability
Risk management
title TRANSITION PROBABILITIES OF CHRONIC KIDNEY DISEASE IN A CARDIOVASCULAR RISK MANAGEMENT PROGRAM
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