TRANSITION PROBABILITIES OF CHRONIC KIDNEY DISEASE IN A CARDIOVASCULAR RISK MANAGEMENT PROGRAM

OBJECTIVES: "De Todo Corazon" (DTC) is a cardiovascular risk management program. The aim of this study was to estimate the transition probabilities of Chronic Kidney Disease (CKD) in patients under program care. METHODS: We followed up a cohort of 55,915 patients with hypertension and / or...

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Veröffentlicht in:Value in health 2017-05, Vol.20 (5), p.A348
Hauptverfasser: Guzman, N Alvis, Machado, P Miranda, Mejia, F Salcedo, Wilches, J Paz, Restrepo, F De la Hoz
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Sprache:eng
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Zusammenfassung:OBJECTIVES: "De Todo Corazon" (DTC) is a cardiovascular risk management program. The aim of this study was to estimate the transition probabilities of Chronic Kidney Disease (CKD) in patients under program care. METHODS: We followed up a cohort of 55,915 patients with hypertension and / or diabetes mellitus between June 2014 and December 2015. The glomerular filtration rate (GFR) was calculated using the Cockcroft Gault formula. A diagnosis of CKD in GFR 65 years and 66.5% were female. The prevalence of hypertension and diabetes mellitus was 96.5% and 36.1%, respectively. At 18 months follow-up, 3.0% of patients with hypertension without diabetes mellitus progressed to CKD (Stage 3B, 4 and 5). 3.8% of patients with hypertension and diabetes mellitus progressed to CKD. The risk of progression of CKD was significantly higher in patients with hypertension with diabetes mellitus (OR: 1.30 CI 95% 1.17-1.45). CONCLUSIONS: The presence of hypertension with diabetes mellitus was significantly associated with progression to CKD over a period of 18 months, independent of baseline GFR.
ISSN:1098-3015
1524-4733
DOI:10.1016/j.jval.2017.05.005