Radiotherapy-associated Euthyroid Graves Ophthalmopathy following Floor-of-mouth Surgery: A Case Report

The thyroid gland is commonly included in the radiation field during treatment of nonthyroidal neoplastic disease of the head and neck. As a result, thyroid abnormalities sometimes occur following external irradiation. We report an unusual case of radiotherapy-associated Graves ophthalmopathy 5 mont...

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Veröffentlicht in:	Ear, nose, & throat journal nose, & throat journal, 2008-09, Vol.87 (9), p.533-536
Hauptverfasser:	Jaber, James J., Thomas, Frank J., Carfrae, Mathew J., Galati, Lisa T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - therapeutic use Autoimmune diseases Cancer Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - radiotherapy Carcinoma, Squamous Cell - surgery Complications and side effects Diagnosis Follow-Up Studies Graves Ophthalmopathy - diagnosis Graves Ophthalmopathy - drug therapy Graves Ophthalmopathy - etiology Humans Hypothyroidism Larynx Male Middle Aged Mouth Floor - pathology Mouth Floor - surgery Mouth Neoplasms - pathology Mouth Neoplasms - radiotherapy Mouth Neoplasms - surgery Oral Surgical Procedures - methods Patients Physical examinations Radiation Injuries - diagnosis Radiation therapy Radiotherapy Radiotherapy Dosage Radiotherapy, Adjuvant Ribonucleic acid Risk Assessment RNA Thyroid diseases Thyroid eye disease Thyroid Function Tests Thyroid gland Tomography Tomography, X-Ray Computed Treatment Outcome
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Zusammenfassung:	The thyroid gland is commonly included in the radiation field during treatment of nonthyroidal neoplastic disease of the head and neck. As a result, thyroid abnormalities sometimes occur following external irradiation. We report an unusual case of radiotherapy-associated Graves ophthalmopathy 5 months after adjuvant external irradiation of the head and neck in a euthyroid patient who had undergone wide local excision of squamous cell carcinoma from the floor of the mouth.
ISSN:	0145-5613 1942-7522
DOI:	10.1177/014556130808700915