Palladium‐Catalyzed Regioselective Cyclocarbonylation of N‐(3‐Phenylprop‐2‐ynyl)anilines with Carbon Monoxide and Alcohols for the Synthesis of Quinoline‐3‐carboxylic Esters

A convenient palladium‐catalyzed regioselective cyclocarbonylation of N‐(3‐phenylprop‐2‐ynyl)anilines with carbon monoxide and alcohols has been developed. This methodology provides a simple and practical approach to various quinoline‐3‐carboxylic esters in good yields with high atom efficiency. Alc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Asian journal of organic chemistry 2018-08, Vol.7 (8), p.1605-1608
Hauptverfasser:	Zhang, Wei, Zhao, Mi‐Na, Chen, Ming, Ren, Zhi‐Hui, Guan, Zhenghui
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Alcohols Carbon monoxide carbonylation Chemical synthesis cyclization Esters Organic chemistry Palladium Quinoline quinolines Regioselectivity synthetic methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A convenient palladium‐catalyzed regioselective cyclocarbonylation of N‐(3‐phenylprop‐2‐ynyl)anilines with carbon monoxide and alcohols has been developed. This methodology provides a simple and practical approach to various quinoline‐3‐carboxylic esters in good yields with high atom efficiency. Alcohols and CO: A palladium‐catalyzed regioselective cyclocarbonylation of N‐(3‐phenylprop‐2‐ynyl)anilines with carbon monoxide and alcohols for the synthesis of quinoline‐3‐carboxylic esters has been developed.
ISSN:	2193-5807 2193-5815
DOI:	10.1002/ajoc.201800301