F(ab')2 Fragments to Overcome Daratumumab Interference in Transfusion Tests: Letter
Daratumumab is an effective agent in multiple myeloma. Its binding of CD38 on red cells causes false positive results on Coombs' blood-compatibility testing. F(ab')2 fragments of daratumumab block this binding and restore the accuracy of the test.
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| Veröffentlicht in: | The New England journal of medicine 2018-07, Vol.379 (1), p.90 |
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| container_issue | 1 |
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| container_title | The New England journal of medicine |
| container_volume | 379 |
| creator | Selleng, Kathleen Gebicka, Patrycja D Thiele, Thomas |
| description | Daratumumab is an effective agent in multiple myeloma. Its binding of CD38 on red cells causes false positive results on Coombs' blood-compatibility testing. F(ab')2 fragments of daratumumab block this binding and restore the accuracy of the test. |
| doi_str_mv | 10.1056/NEJMc1804751 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 2018-07, Vol.379 (1), p.90 |
| issn | 0028-4793 1533-4406 |
| language | eng |
| recordid | cdi_proquest_journals_2081459424 |
| source | EZB Electronic Journals Library; New England Journal of Medicine; ProQuest Central |
| subjects | CD38 antigen Disclosure Immunoglobulins Methods Multiple myeloma Patients |
| title | F(ab')2 Fragments to Overcome Daratumumab Interference in Transfusion Tests: Letter |
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