Imprinted nanobead-based disposable screen-printed potentiometric sensor for highly sensitive detection of 2-naphthoic acid

For the first time, a highly sensitive screen-printed potentiometric sensor based on MIP nanobeads is developed. [Display omitted] •Screen-printed potentiometric sensor based on imprinted polymers is developed for the first time.•Imprinted nanobeads for 2-naphthoic acid are synthesized and used as the sensing materials.•The proposed sensor based on nonequilibrium sensing mechanism exhibits remarkably improved sensitivity. Currently, potentiometric sensors based on various molecularly imprinted polymer (MIP) receptors have been successfully fabricated for detection of organic species. However, almost all of the previously developed potentiometric sensors based on MIPs are in traditional liquid-contact mode in which lower detection limits have been restricted by zero-current transmembrane ion fluxes. Herein, a screen-printed potentiometric sensor for determination of 2-naphthoic acid has been developed. It is based on the MIP nanobeads as the selective receptor and the electrochemically reduced graphene oxide film as the solid contact. Compared with the classical potentiometric sensor, the proposed sensor based on nonequilibrium sensing mechanism exhibits remarkably improved detection sensitivity for 2-naphthoic acid with a low detection limit of 6.9 × 10−11 M.