Disposable MEMS optrode array integrated with single LED for neurostimulation

•An LED-waveguide-based neural probe array using single commercial μLED presented.•System comprises of a disposable MEMS optrode array and a reusable unit with μLED and circuitry.•A 4 × 4 array of 6 mm-long optical fibers are assembled with thermally reflowed square-shaped glass microlenses.•Delivered optical power and light delivery efficiency analyzed. We present an LED-waveguide-based neural probe array with the highest total light power delivery from a single commercial LED. A separable configuration between the LED and the waveguide has been proposed and verified experimentally for a disposable probe tip. The system comprises of a disposable MEMS optrode array and a reusable unit. The optrode array consists of a 4 × 4 array of 6 mm-long optical fibers assembled with thermally reflowed square-shaped glass microlenses. The reusable unit includes a domed top LED and driving circuitry. Measured light delivery efficiency of the optrode array and the total power efficiency of the probe were −10.6 dB and −21.6 dB, respectively.